The Ontario Provincial Police has shut down a section of Main Street in Kingsville after a vehicle struck a building just after midnight Monday morning.
Main Street remains closed between Division Street and Spruce Street while police investigate the cause of the collision.
There were two people in the vehicle at the time. Police say one person suffered life-threatening injuries, while the second occupant's injuries were not as serious.
Members of the Kingsville OPP Detachment, Essex-Windsor Emergency Medical Services, and firefighters responded to the crash around 12:30 a.m.
Anyone with information is asked to call the OPP at 1-888-310-1122, Crime Stoppers at 1-800-222-8477, or leave their tip at www.catchcrooks.com.