An early morning crash will see part of Hwy. 401 near Tecumseh closed until around 10:30am on Saturday.
The OPP say a tractor trailer lost control on the 401 near the 26 mile marker and rolled into the ditch. This caused a load of milk the truck was carrying to spill into the road.
A 25-year-old Mississauga man is in hospital with serious injuries.
Police will be opening two lanes of the 401 by 10:30am, with the remaining lane closed until around 12:30pm.