Environment Canada has issued a winter weather travel advisory for Sarnia-Lambton.
The national weather agency said snow is expected to move into southwestern Ontario Thursday evening, and continue moving northeast overnight.
The heaviest snowfall is most likely to occur during the first few hours, with lighter snowfall expected after that.
Between five and 10 centimetres, two to four inches, of snow is possible.
Motorists are reminded to adjust their driving accordingly and expect road conditions to rapidly deteriorate.