The Bluewater Health Foundation's Dream Home will be given away tonight.
Spokesperson Johanne Tomkins says the draw for the 20th annual lottery is being held at Sarnia Golf and Curing Club.
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Winners will be posted online at www.bluewaterhealthdreamhomelottery.ca by tomorrow (Saturday).
This year's grand prize includes appliances, electronics and furniture is valued at $512,000.
Proceeds benefit the Maternal Infant Child program at Bluewater Health.