Lambton OPP say a mobile home trailer being towed by a pick-up truck collided with a passenger vehicle late Sunday morning.
Police say they responded to the area of Mandaumin Rd. and Churchill Line in Plympton-Wyoming at about 11:30am.
One of the drivers suffered non-life threatening injuries and had to be extricated from the vehicle by firefighters.
Police say the passenger vehicle allegedly failed to stop at the stop sign controlling southbound Mandaumin Rd. at Churchill Line.
An 18-year-old Wallaceburg woman was transported to hospital and is charged with failing to stop for a stop sign.
Sarnia Fire and Rescue, the Petrolia and North Enniskillen Fire Department, and Lambton EMS also responded.